VCAM1 anticorps

N° du produit ABIN7670763

L’anticorps Lapin Polyclonal anti-VCAM1 a été validé pour WB, IHC et ELISA. Il convient pour détecter VCAM1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour VCAM1 anticorps (ABIN7670763)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-VCAM1 anticorps

Fonction: VCAM-1/CD106 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Rat VCAM-1/CD106 protein expressed by Mammalian

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:1000-1:2000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: VCAM-1/CD106

Sujet: CD106,Vcam1,Vcam-1,V-CAM 1,VascuLar ceLL adhesion protein 1,SoLubLe VascuLar CeLL Adhesion MoLecuLe-1,Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.

Poids moléculaire:

Calculated MW: 81kDa

ObservedMW: 75-100kDa

UniProt: P29534

Pathways: Carbohydrate Homeostasis